Doctor's Assessment Included
Every result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.
AMA (Anti-Mitochondrial Antibodies)
AMA testing is particularly relevant for women, as PBC affects women approximately 10 times more often than men. Early detection enables treatment that significantly slows progression.
What It Measures
This test detects and quantifies anti-mitochondrial antibodies in your blood. A positive result, particularly the M2 subtype, is highly specific for primary biliary cholangitis.
Why It Matters
AMA positivity with elevated alkaline phosphatase is sufficient for PBC diagnosis in most cases, often without the need for liver biopsy. Early detection enables treatment to slow disease progression.
When to Test
Testing could be indicated when PBC is suspected: unexplained cholestatic liver enzyme elevation, chronic fatigue with pruritus, or as part of autoimmune liver disease evaluation.
Symptoms
Low Levels
High Levels
Lifestyle Tips
If AMA-positive, consult a hepatologist for further evaluation. Avoid alcohol to protect liver function. Ursodeoxycholic acid (UDCA) is the standard treatment for PBC and can significantly slow disease progression when started early.