Kidney Function
Creatinine, eGFR, and BUN: key kidney markers.
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Included Markers
3 markersA kidney function panel measuring Creatinine, eGFR, and Urea (BUN). These markers reflect how well the kidneys are filtering waste products from the blood.
Why this test?
The kidneys filter waste products from the blood, regulate fluid balance, and help control blood pressure. Changes in kidney function can develop gradually and may not cause symptoms until they are more advanced. Measuring kidney markers can provide early data about how the kidneys are performing.
Who is this test for?
This test may be relevant for women who:
- Want to check kidney function as part of a health assessment
- Take medications that may affect the kidneys
- Have a family history of kidney disease
- Experience symptoms such as changes in urination, swelling, or fatigue
What is tested?
This panel measures three markers:
- Creatinine: a waste product from muscle metabolism; elevated levels may suggest reduced kidney filtration
- eGFR (Estimated Glomerular Filtration Rate): a calculated value that estimates how well the kidneys are filtering; based on creatinine, age, and sex
- Urea (BUN): a waste product from protein metabolism; levels may rise when kidney function is reduced
What can this test tell you?
Creatinine and eGFR together provide an estimate of kidney filtration capacity. A reduced eGFR may suggest that the kidneys are not filtering as efficiently. Elevated urea may reflect increased protein breakdown or reduced kidney clearance. These markers are typically interpreted together and in the context of hydration, diet, and medication use.
How is the sample collected?
The test requires a blood draw at a certified sample point (afnamepunt). There are over 750 locations across the Netherlands. After placing your order, you can select a convenient location and schedule your visit.
When is this test useful?
This test may be considered when:
- You want to assess kidney function as part of a routine check
- You take medications that may affect the kidneys
- You have risk factors for kidney disease
- You want baseline kidney data for future comparison
What do the results mean?
Each marker is shown with your value and the reference range. A normal eGFR generally suggests the kidneys are filtering adequately. A reduced eGFR or elevated creatinine may warrant further investigation. Temporary factors such as dehydration or high protein intake can affect results, so interpretation should be done by a healthcare provider.
Preparation
No specific preparation is needed. Staying well hydrated the day before can help ensure accurate results. No fasting is required.
What happens after the results?
Your results are typically available within a few working days. Each marker is shown with your value, the reference range, and an explanation. These results can be discussed with your healthcare provider to determine whether any follow-up may be appropriate.
From order to report in 4 steps
A hormone test without referral: test when you want, not only when symptoms are severe. No waiting list, just order and go.
Choose your hormone test
Browse our hormone panels and pick what you want tested. Compare markers and prices, or build a custom test.
Receive your lab referral
Within 2-3 hours you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician reviews your hormone values and writes a personal report. On your dashboard within a few business days.
Choose your hormone test
Browse our hormone panels and pick what you want tested. Compare markers and prices, or build a custom test.
Receive your lab referral
Within 2-3 hours you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician reviews your hormone values and writes a personal report. On your dashboard within a few business days.
Always a location near you
With more than 650+ certified phlebotomy points across the Netherlands.
What We Test
This test includes 3 biomarkers to give you a comprehensive health picture.
BUN (blood urea nitrogen) measures the amount of urea nitrogen in your blood, a waste product formed when the body breaks down protein. It is primarily used to evaluate kidney function and can be influenced by diet, hydration status, and liver health.
Learn moreCreatinine is a waste product generated by normal muscle metabolism that is filtered out of the blood by the kidneys. It is widely regarded as the gold standard marker for evaluating kidney function, as consistent production makes it a reliable indicator of filtration efficiency.
Learn moreeGFR (estimated glomerular filtration rate) is a calculated measure of how effectively your kidneys filter waste from the blood. It is the gold standard for diagnosing and staging chronic kidney disease and is derived from blood creatinine or cystatin C levels along with demographic factors.
Learn moreUrea (BUN)
KidneyBUN (blood urea nitrogen) measures the amount of urea nitrogen in your blood, a waste product formed when the body breaks down protein. It is primarily used to evaluate kidney function and can be influenced by diet, hydration status, and liver health.
BUN is a valuable marker for assessing how effectively your kidneys are filtering waste from your blood. Elevated levels may indicate that the kidneys are not functioning optimally, which can be associated with dehydration, kidney disease, or other underlying conditions. Monitoring BUN alongside other kidney markers such as creatinine and eGFR provides a more comprehensive picture of renal health and helps detect potential problems early.
Creatinine
KidneyCreatinine is a waste product generated by normal muscle metabolism that is filtered out of the blood by the kidneys. It is widely regarded as the gold standard marker for evaluating kidney function, as consistent production makes it a reliable indicator of filtration efficiency.
Creatinine is central to assessing kidney health. It is used to calculate the estimated glomerular filtration rate (eGFR), which is the primary measure for staging chronic kidney disease. Early detection of rising creatinine levels can prompt timely intervention, helping to slow the progression of kidney damage. Monitoring creatinine is also important for adjusting medication dosages, as many drugs are cleared by the kidneys.
eGFR (Estimated Glomerular Filtration Rate)
KidneyeGFR (estimated glomerular filtration rate) is a calculated measure of how effectively your kidneys filter waste from the blood. It is the gold standard for diagnosing and staging chronic kidney disease and is derived from blood creatinine or cystatin C levels along with demographic factors.
eGFR is the most important single measure for assessing overall kidney function. It is used internationally to diagnose chronic kidney disease, determine its stage, and guide treatment decisions. Regular eGFR monitoring allows early detection of kidney function decline, often before symptoms appear. This is critical because early intervention can significantly slow the progression of kidney disease and reduce the risk of complications such as cardiovascular disease.
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