Doctor's Assessment Included
Every result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.
Hemoglobin Electrophoresis
Hemoglobin electrophoresis is a laboratory technique that separates and identifies different types of hemoglobin in your blood. It is primarily used to detect hemoglobin variants and diagnose inherited blood disorders such as sickle cell disease and thalassemia.
What It Measures
This test separates the different types of hemoglobin present in your blood based on their electrical charge and size. It identifies the proportions of normal hemoglobin (HbA, HbA2, HbF) and detects abnormal variants such as HbS (sickle hemoglobin) or HbC.
Why It Matters
Identifying hemoglobin variants is important for diagnosing conditions such as sickle cell disease, thalassemia, and other hemoglobinopathies. Early detection allows for appropriate management, genetic counselling, and informed family planning decisions.
When to Test
Testing may be recommended as part of newborn screening, when a hemoglobin disorder is suspected based on symptoms or family history, or before planned anaesthesia. It may also be suggested for individuals from populations with higher prevalence of hemoglobin disorders.
Lifestyle Tips
If you carry a hemoglobin variant, share this information with your healthcare providers. Consider genetic counselling if planning a family, especially if both partners carry a trait. Stay informed about your specific variant and follow recommended screening schedules.
Frequently Asked Questions
What is the difference between having a trait and having the disease?
Carrying a trait (such as sickle cell trait) means you have one copy of the variant gene and typically do not have symptoms. Having the disease means you have two copies, which can cause significant health effects. A healthcare provider or genetic counsellor can explain your specific results.
Should my family members be tested?
If a hemoglobin variant is detected, it may be recommended that close family members also undergo testing. This is especially relevant for siblings, children, and partners who may be planning a family together. Consult a healthcare professional for guidance.