Estradiol (E2) is the primary estrogen guiding your menstrual cycle, fertility, and menopausal transition. Fluctuating levels may indicate changes in ovarian function. Your healthcare provider can help you understand what your results mean for your cycle and overall health.
Doctor's Assessment Included
Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.
Check your own valueThis test measures the concentration of estradiol (E2) in your blood. Estradiol is produced primarily by the ovaries in women and in smaller amounts by the testes and adrenal glands in men. Your healthcare provider may use this result alongside other hormone levels.
Estradiol orchestrates ovulation, supports uterine lining, and influences mood throughout your cycle. During perimenopause, declining levels could suggest approaching menopause. Tracking estradiol with your healthcare provider may offer valuable insight into your reproductive and hormonal health.
Do you have a cycle? Pick the right day
RequiredIf you have a menstrual cycle, count the first day of your period as day 1 and have the draw on day 2 to 5. On hormonal contraception, or without a cycle, any day works.
Your healthcare provider may recommend testing estradiol when investigating irregular menstrual cycles, fertility concerns, menopausal symptoms, or unexplained mood changes. For men, testing could be suggested when evaluating gynecomastia or other hormonal concerns. Consult your provider for personalised timing advice.
Some people may experience hot flashes, night sweats, mood changes, vaginal dryness, or decreased bone density when estradiol levels are low. Fatigue and difficulty concentrating could also suggest reduced estradiol. A healthcare provider can help determine the cause and recommend appropriate support.
Elevated estradiol levels may be associated with bloating, breast tenderness, mood swings, or irregular periods in women. In men, high levels could suggest gynaecomastia or reduced libido. Your healthcare provider can evaluate whether further investigation is needed based on your symptoms.
Low estradiol may indicate menopause, ovarian dysfunction, or eating disorders. Consider hormone replacement therapy if menopausal, or evaluation for underlying conditions.
High estradiol levels may indicate ovarian tumors, pregnancy, or hormone therapy. Consult with a gynecologist or endocrinologist for proper evaluation.
Maintaining a healthy weight, regular physical activity, and a balanced diet rich in fibre and cruciferous vegetables may support healthy estrogen metabolism. Limiting alcohol intake and managing stress could also contribute to hormonal balance. Always discuss lifestyle changes with your healthcare provider.
Estradiol is the strongest form of estrogen, important for reproductive and bone health.
Your provider may suggest testing during fertility evaluation or when experiencing hormonal symptoms.
Diet, exercise, and body weight may influence estradiol. Discuss changes with your healthcare provider.
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This marker is included in the following test panels.
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Articles that explain this value in context.
Medical reviewer
Dr. Naimi oversees the medical standards behind our content and assessments.
Medical policyDoctor's Assessment Included
Every result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.
Estradiol (E2)
€34,-
