Kidney Function
Creatinine, eGFR, and BUN: key kidney markers.
Every result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.
BUN is a kidney function marker that can be influenced by hormonal changes throughout a woman's life. During pregnancy, BUN levels typically decrease due to increased blood volume and kidney filtration, while hormonal shifts during menopause may affect kidney function over time.
BUN measures the concentration of urea nitrogen in your blood. Urea is a waste product created in the liver when proteins are metabolised. It travels through the bloodstream to the kidneys, where it is filtered out and excreted in urine.
Because both the liver and kidneys play a role in urea processing, BUN levels can reflect the health of both organs. However, it is most commonly used as an indicator of kidney function.
BUN is a valuable marker for assessing how effectively your kidneys are filtering waste from your blood. Elevated levels may indicate that the kidneys are not functioning optimally, which can be associated with dehydration, kidney disease, or other underlying conditions.
Monitoring BUN alongside other kidney markers such as creatinine and eGFR provides a more comprehensive picture of renal health and helps detect potential problems early.
BUN testing is commonly included in routine health screenings and comprehensive metabolic panels. It may also be recommended when symptoms of kidney dysfunction are present, such as changes in urination patterns, persistent fatigue, or unexplained swelling.
Additional testing may be appropriate for individuals with risk factors for kidney disease, including diabetes, high blood pressure, a family history of kidney problems, or long-term use of certain medications.
Low urea may indicate liver problems or overhydration. Consult your healthcare provider if symptomatic.
Elevated urea may indicate kidney dysfunction or dehydration. Consider hydration and kidney function evaluation.
Stay well hydrated throughout the day, as dehydration is a common cause of elevated BUN levels. Maintain a balanced diet with moderate protein intake, as very high protein consumption can increase BUN.
Manage blood pressure and blood sugar levels carefully, as both hypertension and diabetes are leading causes of kidney damage. Limit the use of over-the-counter pain medications such as NSAIDs, which may affect kidney function over time.
This marker is included in the following test panels.
Creatinine, eGFR, and BUN: key kidney markers.
Comprehensive metabolic panel: electrolytes, kidney, liver, glucose, HbA1c, and protein.