HOMA-IR test based on fasting glucose and insulin
Assess insulin resistance, often linked to hormonal balance and PCOS, with your HOMA-IR score.
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Included Markers
3 markersMaybe you notice stubborn fatigue, cravings or shifts in your weight, and wonder what your body is trying to tell you. Insulin plays a role in this more often than you might think. A HOMA-IR test can help you get a little more grip on it.
HOMA-IR is a calculation based on your fasting glucose and fasting insulin. Together these values give an impression of how sensitive your body is to insulin, something closely tied to your hormonal balance.
Why this test?
Insulin resistance often develops gradually and without clear signals. A HOMA-IR test looks at the relationship between your fasting glucose and fasting insulin, so you get a picture of how your body handles sugar and insulin.
For women this is especially interesting, because insulin sensitivity is closely woven into your hormonal balance. Think of your cycle, your energy and symptoms that are sometimes linked to PCOS.
Who is this test for?
This insulin resistance test can be interesting if you are curious about how your body handles insulin. For example if you deal with energy dips, find it hard to lose weight, or have questions around PCOS.
Also if insulin resistance runs in your family, or if you simply want a factual starting point, an insulin test can give you a little more insight. You decide whether and when you want this measured.
What is tested?
This test looks at three related values in your blood:
- Glucose (Fasting): your blood sugar level after a period of fasting, a baseline measure of how your body processes sugar.
- Insulin (Fasting): the amount of insulin in your blood while fasting, showing how much effort your body puts into keeping your glucose stable.
- HOMA-IR: a calculated score based on your fasting glucose and insulin that can give an impression of your insulin sensitivity.
Together these three form the basis for your HOMA-IR score.
What can this test tell you?
Your HOMA-IR score can give an impression of how sensitive your body currently is to insulin. A higher score may point to reduced insulin sensitivity, while a lower score can fit with normal sensitivity.
It remains a single snapshot and not a diagnosis. The outcome can help you look, together with a doctor, at what the numbers might mean in your situation.
How is the sample collected?
This test requires a small blood draw at a certified lab. In the Netherlands you can choose from 700+ sample points, so there is often one near you.
After ordering, you pick a location and a moment that suits you. The draw usually takes only a few minutes, and you do not need a referral from your GP.
When is this test useful?
Measuring insulin resistance can be valuable at different moments, for example:
- when you have questions around PCOS or other hormonal symptoms
- when losing weight feels hard despite your efforts
- when you deal with cravings, energy dips or fluctuating blood sugar
- when you simply want a factual view of your insulin sensitivity
An insulin blood test like this gives you something tangible to work with.
What do the results mean?
Your result shows your fasting glucose, your fasting insulin and your calculated HOMA-IR score, each with a reference range. What counts as usual can vary slightly by laboratory.
A score within the range usually fits with normal insulin sensitivity, while a higher score may point to more insulin resistance. A doctor helps you place these numbers in the right context.
Preparation
For a reliable HOMA-IR score it is important that you are fasting. That usually means eating nothing for around eight to twelve hours before the blood draw and drinking only water.
For that reason, it helps to plan your appointment in the morning, so you spend most of the fasting window while you sleep. When scheduling your draw you will find clear instructions about this.
What happens after the results?
Your result is usually available online within a few working days. Each value is shown clearly with a reference range and an explanation, so you understand what you see.
Every blood test result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.
Frequently Asked Questions
From order to report in 4 steps
A hormone test without referral: test when you want, not only when symptoms are severe. No waiting list, just order and go.
Choose your hormone test
Browse our hormone panels and pick what you want tested. Compare markers and prices, or build a custom test.
Receive your lab referral
Within 1 business day you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed from the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician reviews your hormone values and writes a personal report. On your dashboard within a few business days.
Choose your hormone test
Browse our hormone panels and pick what you want tested. Compare markers and prices, or build a custom test.
Receive your lab referral
Within 1 business day you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed from the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician reviews your hormone values and writes a personal report. On your dashboard within a few business days.
Always a location near you
With 700+ certified phlebotomy points across the Netherlands.
What We Test
This test includes 3 biomarkers to give you a comprehensive health picture.
Fasting glucose measures the level of sugar (glucose) in your blood after an overnight fast. It is one of the primary tests used to screen for and monitor diabetes and pre-diabetes.
Learn moreHOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a calculated index derived from fasting glucose and fasting insulin levels. It is widely used to estimate insulin resistance, a condition where the body's cells respond less effectively to insulin.
Learn moreFasting insulin measures the amount of insulin in your blood after an overnight fast. It helps assess how efficiently your body manages blood sugar and can reveal insulin resistance before glucose levels become abnormal.
Learn moreGlucose (Fasting)
MetabolicFasting glucose measures the level of sugar (glucose) in your blood after an overnight fast. It is one of the primary tests used to screen for and monitor diabetes and pre-diabetes.
Learn moreHOMA-IR
MetabolicHOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a calculated index derived from fasting glucose and fasting insulin levels. It is widely used to estimate insulin resistance, a condition where the body's cells respond less effectively to insulin.
Learn moreInsulin (Fasting)
MetabolicFasting insulin measures the amount of insulin in your blood after an overnight fast. It helps assess how efficiently your body manages blood sugar and can reveal insulin resistance before glucose levels become abnormal.
Learn moreRelated biomarkers
Biomarkers often explored alongside this test for a fuller picture.
C-Peptide
C-Peptide assesses insulin production, which can be affected by hormonal conditions like PCOS. Understanding your levels supports metabolic and hormonal health awareness.
HbA1c (Glycated Hemoglobin)
HbA1c provides a long-term blood sugar picture, important for women managing PCOS, gestational diabetes, or metabolic changes during menopause.
Lactate
Lactate levels reflect metabolic efficiency and tissue oxygenation. Monitoring supports comprehensive metabolic health insight for women.
Leptin
Leptin testing measures the appetite-regulating hormone. For women, leptin interacts with reproductive hormones and may be relevant to menstrual regularity, fertility, and weight management.
Uric Acid
Uric acid levels can be influenced by hormonal factors. While gout is less common in premenopausal women, monitoring supports comprehensive metabolic health awareness.
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