Insulin Resistance (HOMA-IR)

HOMA-IR is a calculated score, not a separate measurement. It is derived from two fasting markers: fasting glucose and fasting insulin, using the formula (glucose × insulin) / 22.5. A higher score points towards more insulin resistance; a lower score towards better insulin sensitivity.

Insulin resistance often develops quietly. Fasting insulin can rise to keep glucose normal long before fasting glucose itself moves, so HOMA-IR can surface metabolic change earlier than a glucose test alone. This panel is aimed at understanding insulin resistance and its link to hormonal health and PCOS.

The panel measures and reports three things:

• Glucose (fasting) — your fasting blood sugar
• Insulin (fasting) — the hormone that moves glucose into cells
• HOMA-IR — the calculated insulin-resistance score from the two values above

The test is a blood draw at a certified sample point (afnamepunt), with over 750 locations across the Netherlands. After ordering, you choose a convenient location and plan your visit. The draw is performed by trained professionals.

Both glucose and insulin must be measured fasting, so this test requires fasting. Do not eat or drink anything except water for 8 to 12 hours before the blood draw, and avoid alcohol the evening before. Take your blood drawn in the morning where possible.

Results are usually available within a few working days. Glucose and insulin are shown with their reference ranges, and HOMA-IR with its interpretation band. These are intended to be discussed with your doctor, who can interpret them in the context of your personal situation.