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Liver

Alkaline Phosphatase: Normal Values and What a High Result Means

ALP helps evaluate liver and bone health. Levels naturally rise during pregnancy and can change with menopause-related bone density shifts.

Doctor's Assessment Included

Reference Ranges

See the value that applies to you:

Choose male or female — this range differs by sex.

Enter your age — this range changes with age.

This range also depends on context such as cycle phase or sample material; the highlighted rows apply to your group.

Your reference range
u/l
38 209 u/l
Reference ranges by group, in u/l
Female · 6–12 years 107–209 u/l
107 209
Female · 13–18 years 44–149 u/l
44 149
Female · 19–50 years 38–123 u/l
38 123
Female · 51–65 years 48–142 u/l
48 142
Female · 66–80 years 47–138 u/l
47 138
Female · 81 years and older 45–146 u/l
45 146
38 209 u/l

Source: NVKC Reference population: Nederlandse huisartsenpopulatie (NUMBER, n=7.574.327)

Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.

Check your own value

What It Measures

This test measures the total ALP enzyme activity in your blood. Elevated levels may originate from the liver, bone, or other tissues, and further testing may be needed to determine the source.

Why It Matters

ALP is a useful screening marker for liver and bone conditions. Elevated levels may indicate bile duct obstruction, liver disease, or bone disorders. Consult your healthcare provider for interpretation.

When to Test

ALP is commonly included in liver function panels and routine blood work. Testing may be specifically ordered to investigate liver symptoms, bone pain, or abnormal imaging findings.

Symptoms

Low Levels

Low ALP is uncommon but may be associated with certain nutritional deficiencies or rare genetic conditions. Discuss low levels with your healthcare provider.

High Levels

Elevated ALP may be associated with liver problems (jaundice, abdominal pain, dark urine), bone disorders (bone pain, fractures), or during normal growth and pregnancy.

Recommendations

Female

If Low

Low ALP is generally not concerning.

If High

Elevated ALP may indicate bile duct or bone problems. Consider further evaluation.

Lifestyle Tips

Maintain liver health by limiting alcohol, eating a balanced diet, and avoiding unnecessary medications. Support bone health through adequate calcium, vitamin D, and weight-bearing exercise.

Frequently Asked Questions

Can ALP be high during pregnancy?
Yes, ALP naturally rises during pregnancy, particularly in the third trimester, as the placenta produces ALP. This is generally normal.
How can I tell if elevated ALP is from liver or bone?
Additional tests such as GGT (which rises only with liver issues) or ALP isoenzyme testing can help distinguish the source. Your healthcare provider can order these.
Is ALP elevation always a concern?
Not always. ALP can be elevated during growth in children, pregnancy, and after bone fracture healing. Context is important, and your healthcare provider can advise.

Test Products

This marker is included in the following test panels.

ALP (Alkaline Phosphatase)

€8,-