Graves' Disease Blood Test - Thyroid Function Panel
TSH, Free T4, Free T3, and TSH Receptor Antibodies to help assess Graves' disease.
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Included Markers
4 markersA panel measuring thyroid function markers alongside TSH Receptor Antibodies, which may be associated with Graves' disease. This combination provides data about both thyroid function and potential autoimmune involvement.
Why this test?
Graves' disease is an autoimmune condition in which antibodies stimulate the thyroid to produce excess hormone. Testing for TSH Receptor Antibodies alongside standard thyroid function markers can help determine whether an autoimmune mechanism may be involved in thyroid overactivity.
Who is this test for?
This test may be relevant for women who:
- Experience symptoms associated with an overactive thyroid, such as rapid heartbeat, weight loss, tremor, or heat sensitivity
- Have been told they may have Graves' disease and want to measure associated antibodies
- Have a family history of autoimmune thyroid conditions
- Want data to discuss thyroid autoimmunity with their healthcare provider
What is tested?
This panel measures four markers:
- TSH: typically suppressed in Graves' disease due to excess thyroid hormone production
- Free T4: the primary thyroid hormone; may be elevated when the thyroid is overactive
- Free T3: the more active thyroid hormone; may also be elevated
- TSH Receptor Antibodies: antibodies that bind to the TSH receptor and may stimulate the thyroid; their presence is associated with Graves' disease
What can this test tell you?
Suppressed TSH with elevated Free T4 or T3 may suggest thyroid overactivity. The presence of TSH Receptor Antibodies can help distinguish Graves' disease from other causes of hyperthyroidism. This distinction may be relevant because Graves' disease involves an autoimmune mechanism that can influence treatment decisions. Results should be interpreted by a healthcare provider.
How is the sample collected?
The test requires a blood draw at a certified sample point (afnamepunt). There are over 750 locations across the Netherlands. After placing your order, you can select a convenient location and schedule your visit.
When is this test useful?
This test may be considered when:
- You experience symptoms that may suggest an overactive thyroid
- You want to check for TSH Receptor Antibodies associated with Graves' disease
- You have a known thyroid condition and want to assess autoimmune involvement
- A healthcare provider has suggested testing for Graves' disease markers
What do the results mean?
Each marker is shown with your value and the reference range. Suppressed TSH with elevated Free T4 or T3, combined with positive TSH Receptor Antibodies, may be consistent with Graves' disease. However, the interpretation requires clinical context, and these results should be discussed with a healthcare provider who can consider your full symptom picture and medical history.
Preparation
No specific preparation is needed. No fasting is required. If you take thyroid medication, discuss timing with your healthcare provider.
What happens after the results?
Your results are typically available within a few working days. Each marker is shown with your value, the reference range, and an explanation. These results can be discussed with your healthcare provider to determine whether further evaluation or treatment may be appropriate.
From order to report in 4 steps
Test when you want, not only when symptoms are severe. No waiting list, no referral needed. Just order and go.
Choose your hormone test
Browse our hormone panels and pick what you want tested. Compare markers and prices, or build a custom test.
Receive your lab referral
Within 2-3 hours you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician reviews your hormone values and writes a personal report. On your dashboard within a few business days.
Choose your hormone test
Browse our hormone panels and pick what you want tested. Compare markers and prices, or build a custom test.
Receive your lab referral
Within 2-3 hours you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician reviews your hormone values and writes a personal report. On your dashboard within a few business days.
Always a location near you
With more than 450+ certified phlebotomy points across the Netherlands.
What We Test
This test includes 4 biomarkers to give you a comprehensive health picture.
TSH, or thyroid-stimulating hormone, is produced by the pituitary gland and controls the thyroid. It is the most commonly used blood value to assess thyroid function. An abnormal TSH level can indicate an underactive thyroid (hypothyroidism) or an overactive thyroid (hyperthyroidism). Thyroid problems are common — especially in women — and can cause a wide range of symptoms, from fatigue and weight gain to palpitations and nervousness.
Learn moreTSH receptor antibodies (TRAb) target the TSH receptor on thyroid cells. These antibodies are primarily associated with Graves' disease and may either stimulate or block thyroid function. Your healthcare provider can help interpret what your TRAb results mean for your thyroid health.
Learn moreFree T4 (thyroxine) is the main hormone produced by the thyroid gland. It may serve as a precursor that your body converts into the more active T3. Healthcare providers often consider Free T4 a primary indicator of thyroid gland output.
Learn moreFree T3 (triiodothronine) is considered the most active thyroid hormone. It may play a key role in regulating metabolism, energy production, and body temperature. Healthcare providers often assess Free T3 alongside other thyroid markers for a comprehensive picture.
Learn moreTSH (Thyroid Stimulating Hormone)
ThyroidTSH, or thyroid-stimulating hormone, is produced by the pituitary gland and controls the thyroid. It is the most commonly used blood value to assess thyroid function. An abnormal TSH level can indicate an underactive thyroid (hypothyroidism) or an overactive thyroid (hyperthyroidism). Thyroid problems are common — especially in women — and can cause a wide range of symptoms, from fatigue and weight gain to palpitations and nervousness.
The thyroid affects virtually every organ in your body. The hormones it produces (T3 and T4) regulate your metabolism, heart rate, body temperature, energy level, and even your mood. When thyroid function is disrupted, the effects can be wide-ranging. Hypothyroidism (underactive) is the most common thyroid condition, affecting an estimated 5% of adults, with a clear predominance in women. It is often caused by the autoimmune condition Hashimoto's disease. Symptoms develop gradually and are therefore often recognised late. Hyperthyroidism (overactive) is less frequent but can be more serious. Graves' disease is the most common cause. Untreated, it can lead to heart rhythm disorders and bone loss. For women trying to conceive, the TSH value is particularly relevant, as suboptimal thyroid function can affect fertility and pose risks during pregnancy. A TSH below 2.5 mU/L is often used as a target in this context.
TSH Receptor Antibodies
ThyroidTSH receptor antibodies (TRAb) target the TSH receptor on thyroid cells. These antibodies are primarily associated with Graves' disease and may either stimulate or block thyroid function. Your healthcare provider can help interpret what your TRAb results mean for your thyroid health.
TRAb testing may help your healthcare provider diagnose Graves' disease, predict the likelihood of relapse after treatment, and make decisions about ongoing management. In pregnant women, TRAb levels may be monitored as these antibodies can cross the placenta and potentially affect the baby's thyroid function.
Free T4 (Thyroxine)
ThyroidFree T4 (thyroxine) is the main hormone produced by the thyroid gland. It may serve as a precursor that your body converts into the more active T3. Healthcare providers often consider Free T4 a primary indicator of thyroid gland output.
Free T4 may help your healthcare provider determine whether your thyroid gland is producing adequate hormone levels. Some experts consider it one of the most informative markers for detecting both overactive and underactive thyroid conditions early.
Free T3 (Triiodothyronine)
ThyroidFree T3 (triiodothronine) is considered the most active thyroid hormone. It may play a key role in regulating metabolism, energy production, and body temperature. Healthcare providers often assess Free T3 alongside other thyroid markers for a comprehensive picture.
Free T3 may help your healthcare provider evaluate how well your thyroid is functioning at a cellular level. Some experts suggest it can reveal conversion issues that other thyroid tests might miss, potentially offering a more complete understanding of thyroid health.
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