Insulin Resistance (HOMA-IR)
Assess insulin resistance, often linked to hormonal balance and PCOS, with your HOMA-IR score.
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Included Markers
3 markersHOMA-IR (Homeostatic Model Assessment of Insulin Resistance) estimates insulin resistance from a fasting blood sample. It is a simple, well-established way of understanding insulin resistance and its link to hormonal health and PCOS.
What is HOMA-IR?
HOMA-IR is a calculated score, not a separate measurement. It is derived from two fasting markers: fasting glucose and fasting insulin, using the formula (glucose × insulin) / 22.5. A higher score points towards more insulin resistance; a lower score towards better insulin sensitivity.
Why this test?
Insulin resistance often develops quietly. Fasting insulin can rise to keep glucose normal long before fasting glucose itself moves, so HOMA-IR can surface metabolic change earlier than a glucose test alone. This panel is aimed at understanding insulin resistance and its link to hormonal health and PCOS.
What is tested?
The panel measures and reports three things:
- Glucose (fasting) — your fasting blood sugar
- Insulin (fasting) — the hormone that moves glucose into cells
- HOMA-IR — the calculated insulin-resistance score from the two values above
How is the sample collected?
The test is a blood draw at a certified sample point (afnamepunt), with over 750 locations across the Netherlands. After ordering, you choose a convenient location and plan your visit. The draw is performed by trained professionals.
Preparation — fasting required
Both glucose and insulin must be measured fasting, so this test requires fasting. Do not eat or drink anything except water for 8 to 12 hours before the blood draw, and avoid alcohol the evening before. Take your blood drawn in the morning where possible.
What happens after the results?
Results are usually available within a few working days. Glucose and insulin are shown with their reference ranges, and HOMA-IR with its interpretation band. These are intended to be discussed with your doctor, who can interpret them in the context of your personal situation.
Frequently Asked Questions
From order to report in 4 steps
A hormone test without referral: test when you want, not only when symptoms are severe. No waiting list, just order and go.
Choose your hormone test
Browse our hormone panels and pick what you want tested. Compare markers and prices, or build a custom test.
Receive your lab referral
Within 2-3 hours you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician reviews your hormone values and writes a personal report. On your dashboard within a few business days.
Choose your hormone test
Browse our hormone panels and pick what you want tested. Compare markers and prices, or build a custom test.
Receive your lab referral
Within 2-3 hours you'll receive an email from ZorgDomein with a barcode. Orders outside business hours are processed the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician reviews your hormone values and writes a personal report. On your dashboard within a few business days.
Always a location near you
With more than 650+ certified phlebotomy points across the Netherlands.
What We Test
This test includes 3 biomarkers to give you a comprehensive health picture.
Fasting glucose measures the level of sugar (glucose) in your blood after an overnight fast. It is one of the primary tests used to screen for and monitor diabetes and pre-diabetes.
Learn moreFasting insulin measures the amount of insulin in your blood after an overnight fast. It helps assess how efficiently your body manages blood sugar and can reveal insulin resistance before glucose levels become abnormal.
Learn moreHOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a calculated index derived from fasting glucose and fasting insulin levels. It is widely used to estimate insulin resistance, a condition where the body's cells respond less effectively to insulin.
Learn moreGlucose (Fasting)
MetabolicFasting glucose measures the level of sugar (glucose) in your blood after an overnight fast. It is one of the primary tests used to screen for and monitor diabetes and pre-diabetes.
Fasting glucose is a cornerstone of metabolic health assessment. Elevated levels may indicate pre-diabetes or diabetes, while very low levels can also be clinically significant. Consult your healthcare provider for interpretation.
Insulin (Fasting)
MetabolicFasting insulin measures the amount of insulin in your blood after an overnight fast. It helps assess how efficiently your body manages blood sugar and can reveal insulin resistance before glucose levels become abnormal.
Fasting insulin can detect insulin resistance years before diabetes develops. Early detection allows for lifestyle interventions that may prevent progression. Consult your healthcare provider for personalised advice.
HOMA-IR
MetabolicHOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a calculated index derived from fasting glucose and fasting insulin levels. It is widely used to estimate insulin resistance, a condition where the body's cells respond less effectively to insulin.
Insulin resistance is often linked to an increased risk of type 2 diabetes, metabolic syndrome, cardiovascular disease, and other metabolic conditions. HOMA-IR can help identify insulin resistance in its early stages, when lifestyle interventions may be most effective.
Related biomarkers
Biomarkers often explored alongside this test for a fuller picture.
C-Peptide
C-Peptide assesses insulin production, which can be affected by hormonal conditions like PCOS. Understanding your levels supports metabolic and hormonal health awareness.
HbA1c (Glycated Hemoglobin)
HbA1c provides a long-term blood sugar picture, important for women managing PCOS, gestational diabetes, or metabolic changes during menopause.
Lactate
Lactate levels reflect metabolic efficiency and tissue oxygenation. Monitoring supports comprehensive metabolic health insight for women.
Uric Acid
Uric acid levels can be influenced by hormonal factors. While gout is less common in premenopausal women, monitoring supports comprehensive metabolic health awareness.
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