Funkcja nerek
Kreatynina, eGFR i mocznik (BUN): kluczowe biomarkery nerek.
Bilirubin is a bile pigment that forms when red blood cells are broken down: first haemoglobin is released, which is then broken down into bilirubin. The liver converts bilirubin into conjugated bilirubin, which leaves the body through the bowel and the stool.
Only that converted bilirubin dissolves in water and can end up in the urine, and urine normally contains no detectable amount of bilirubin. According to an American review from 2022, a positive dipstick is a reason to investigate the liver and bile ducts, and whether there is bilirubin in the urine only a urine test shows.
Urine bilirubin has no unit: the result is negative or positive. Star-SHL expects 'Negatief' (negative) on its urine strip, Unilabs 'n.aant.' (not detectable) on a urine bilirubin test that can no longer be ordered.
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The urine bilirubin test is a dipstick that shows whether conjugated bilirubin, the form the liver has converted, is present in a urine sample. According to a 2005 review, unconjugated bilirubin does not dissolve in water and cannot pass through the glomeruli, the filters of the kidney.
Star-SHL preferably asks for morning urine. Unilabs reports that the separate urine bilirubin test can no longer be ordered, and its current urine strip does not include bilirubin.
Urine bilirubin matters because, according to an American review from 2022, a positive strip can point to a condition of the liver or bile ducts: that review's table names blockage of the bile ducts and liver disease. According to the NVKC, the urine strip for bilirubin is of limited value, because more sensitive and more specific tests exist in blood.
According to the NVKC, substances that do not belong in urine can end up there because the kidneys do not work properly, but also because they are present (in raised amounts) in the blood.
Urine bilirubin is measured on a urine strip, at Star-SHL preferably in morning urine. With signs of liver problems, according to the NVKC, the doctor usually orders a bilirubin test in blood, together with other liver function tests.
A negative urine bilirubin result is the expected result, because according to a 2005 review urine normally contains no detectable bilirubin. A negative strip can also be falsely negative: a 2022 review names vitamin C, urine left in the light for a long time and selenium as causes.
According to a 2017 review, Gilbert syndrome and disorders in which red blood cells are destroyed (haemolysis) raise the unconjugated bilirubin, and according to the 2005 review that form does not dissolve in water and cannot pass through the filters of the kidney.
A positive urine bilirubin result can point to liver disease or a blockage of the bile ducts, and according to a 2022 review it is a reason for further investigation of the liver and bile ducts. According to a 2017 review, people with a blocked bile duct can have, among other things, fever, itching, abdominal pain, weight loss, dark urine and pale stools.
According to the NVKC, a yellow skin or yellow whites of the eyes point to jaundice, from more bilirubin due to abnormalities in the liver or the bile drainage. According to the 2022 review, the medicine phenazopyridine can give a falsely positive strip.
With a positive urine bilirubin result, according to the NVKC there are better tests in blood, which are more sensitive and more specific than the strip. Long-term use of alcohol is on the NVKC's list of causes of a raised bilirubin in blood.
No, according to a 2005 review urine normally contains no detectable amount of bilirubin, and Star-SHL expects 'Negatief' (negative) on its urine strip.
The difference between bilirubin in urine and in blood is that, according to reviews from 2005 and 2022, only conjugated bilirubin, the form the liver has converted, can end up in urine. According to the NVKC, blood tests for bilirubin are more sensitive and more specific than the urine strip.
Yes, according to a 2022 review vitamin C can make a bilirubin strip falsely negative and the medicine phenazopyridine can make it falsely positive. That review also names selenium and urine left in the light for a long time as causes of a falsely negative result.
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Te panele mierzą wartości z tej samej kategorii co ten biomarker.
Kreatynina, eGFR i mocznik (BUN): kluczowe biomarkery nerek.
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Konsultant medyczny
Dr Naimi nadzoruje standardy medyczne naszych treści i ocen.
Polityka medycznaOcena lekarza w cenie
Każdy wynik zawiera profesjonalną ocenę lekarza wpisanego do holenderskiego rejestru BIG. W sprawie decyzji dotyczących leczenia omów swoje wyniki ze swoim lekarzem rodzinnym.
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