نسبة الكوليسترول إلى HDL: شرح مبسط

The cholesterol/HDL ratio is the ratio between total cholesterol and HDL cholesterol, two values the laboratory measures separately. According to the NVKC, the total cholesterol test measures both LDL cholesterol and HDL cholesterol without distinguishing between the two forms. Star-SHL, Unilabs and Diagnostiek voor U each give a limit for cholesterol and for HDL cholesterol, but none of the three publishes a limit for the ratio itself.

According to the NVKC, the cholesterol/HDL ratio is a usual way of looking at cholesterol, but according to the NVKC it is very important to look at the results of the separate tests as well. The NHG, the Dutch college of general practitioners, no longer estimates the risk of cardiovascular disease in SCORE2 on the basis of the total cholesterol/HDL cholesterol ratio, but on the basis of non-HDL cholesterol: total cholesterol minus HDL cholesterol. The NHG chooses this because non-HDL cholesterol includes the cholesterol in all apoB-containing, bad lipoproteins.

According to the NVKC, the cholesterol/HDL ratio is preferably measured at least 6 weeks after a pregnancy, because HDL cholesterol is often abnormal in pregnancy. The ratio follows from the lipid profile, which according to the NVKC usually includes total cholesterol, triglycerides and separate HDL and LDL cholesterol. According to the NVKC, for testing all the fats it is important that blood is taken fasting, after 12 hours without eating or drinking, because LDL and triglycerides in particular are strongly affected by food. According to the NHG, non-HDL cholesterol can also be measured non-fasting.